The Effect of Enzyme Induction and Enzyme Inhibition on the Toxicity and Efficacy of the Prescribed Drugs- a Review

The development of the novel therapeutic agents or drugs will be widely affected by Parameters related to the chemistry (structure activity relationship), Pharmacology (mechanism of action of the drug) and the Pharmacokinetic profile of the drug (metabolism characteristics) will play an important role. Before a drug is newly launched in the market various pre clinical studies has to be undertaken to determine the efficacy, toxicological and the pharmacokinetic profile of the drug. In the clinical studies where the drugs has to be tested on the living beings, much concentration has been done on the safety profile of the drug which is the only defined factor for its approval and use in the market.